0.5%罗哌卡因腰硬联合麻醉在肛肠手术的临床应用

毕业论文

关键词:罗哌卡因;布比卡因;腰麻-硬膜外联合麻醉

中图分类号:R614

摘要:目的 观察0.5%罗哌卡因腰硬联合麻醉在肛肠手术的应用及术后恢复情况。方法 随机选取择期行肛肠手术的患者48例,分为2组,罗哌卡因(RP)组和布比卡因(组),腰硬联合麻醉下,蛛网膜下腔给药。RP组蛛网膜下腔注入0.5%罗哌卡因2ml,BP组注入0.5%布比卡因2ml。结果 RP组的感觉阻滞与运动阻滞的起效时间均慢于BP组,最高感觉阻滞平面与最大运动阻滞程度均低于BP组,感觉阻滞持续时间与BP组无差异,运动阻滞持续时间则短于BP组。2组患者均未于硬膜外腔追加药物,均安全满意完成手术。结论 0.5%罗哌卡因腰硬联合麻醉是肛肠科手术安全可靠的麻醉选择。

The clinical use of 0.5% ropivacaine of combined spinal epidural anaesthesia in the anus intestine disease operation

Abstract:Aim To investigate the clinical use of 0.5% ropivacaine of combined epidural anaesthesia in the anus intestine disease operation.Methods 48 patients who had anus intestine disease were randomly assigned to 2 groups(24 patients in every group):ropivacaine(RP) group and bupivacaine(BP) group,using combined epidural anaesthesia,ropivacaine and bupivacaine were injected into subarachnoind.Using 0.5% ropivacaine 2ml spinal anaesthesia in RP group and 0.5% bupivacaine 2ml in BP group.Results The oneset time of sensory and motor blocks in RP group were longer than that of BP group,the height of sensory block and the degree of motor block in RP group were lower than that of BP group, the duration of motor block in RP was shorter than that of BP,the duration of sensory block of the two groups were not siginificantly different.All patients were not used epidural anaesthesia additionally and completed surgery safely and satisfactorily.Conclusion 0.5% ropivacaine of combined epidural anaesthesia is the safe choice in the anus intestine disease operation

Key words:ropivacaine;bupivacaine; combined spinal epidural anaesthesia

本实验选用0.5%罗哌卡因应用于腰硬联合麻醉,观察其对肛门会阴区阻滞完善程度,平面的扩散,最大阻滞平面,最大阻滞时间,并与布比卡因相比较,为临床肛肠手术麻醉选用药物提供理论依据。

1.临床资料 1.2麻醉方法 患者入室建立静脉通道输注林格式液,监测血压、心电图、心率、血氧饱和度,取左侧卧位,腰3-4间隙穿刺,脑脊液流出后,以0.1ml/s速度分别推注0.5%罗哌卡因液或0.5%布比卡因溶液2ml。之后向上置入硬膜外导管3cm。观察并记录生命体征及麻醉平面。 1.4 统计学处理 数据用均数 标准差表示,,采用spss11.5统计软件包进行数据处理,组间比较采用Student’s-t检验,α=0.05。

2.结果 表1 RP组和BP组感觉阻滞比较

组别 感觉阻滞起效时间 最高感觉阻滞平面 感觉阻滞持续时间

(min) 胸椎脊髓节段 (min) BP组 1.6 0.5 10 1.5 288 51

组间比较采用student’-t检验,*P<0.05

表2 RP组和BP组运动阻滞比较

组别 运动阻滞起效时间 最大运动阻滞程度 运动阻滞持续时间

(min) Bromage评分 (min)

RP组 11 3* 1.9 1.4* 118 36* 组间比较采用student’-t检验,*P<0.05

3. 讨论 参考文献

1. 王艳姝,周春燕,王凡. 罗比卡因和布比卡因在硬脊膜外阻滞中的应用.吉林大学学报(医学版)2002,5:550-552.

2.肖少华,罗振中,夏敏等. 罗哌卡因与布比卡因用于蛛网膜下腔阻滞的疗效比较.医药导报2005,1:43-44. 4.Gautier PE,De Kock M,Van Steenberge A,et al.Intrathecal ropivacaine for ambulatory surgery:a comparison between intrathecal bupivacaine and intrathecal ropivacaine for knee arthroscopy.Anesthesiology,1999,91

(5):1239–1245.

5.Malinovsky JM,Charles F,Kick O,et al.Intrathecal anesthesia:ropivacaine versus bupivacaine.Anesth Analg,2000,91

(6):1457–1460.

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页面更新:2024-05-01

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